Pan-serotype reduction in progression of Streptococcus pneumoniae to otitis media after rollout of pneumococcal conjugate vaccines Academic Article uri icon


  • Pneumococcal progression from carriage to otitis media declined following rollout of PCV7/13 in Israel. Vaccine-targeted and non-vaccine serotypes showed lower progression rates. Early-life otitis media episodes, historically often caused by PCV7/13-targeted serotypes, may exacerbate children's future susceptibility to otitis media.

publication date

  • January 1, 2017