- Background: Epidemics and pandemics have had a great impact on the course of human history. As such emergence and re-emergence of diseases of high risk to the individual, and/or the community, are of specific interest and concern to public health systems, whether they be in developed or developing countries. Ebola viruses represent prime examples of such emerging pathogens. Ebola outbreaks are unpredictable, with high severity and fatality rates. This high case fatality rate of Ebola virus infection and the lack of approved vaccines and therapeutics resulted in classification of Ebola viruses as biosafety level 4 pathogens and potential bioweapons by the WHO and the CDC.