Bio-amplifying lab-on-a-chip for antipsychotic clozapine treatment monitoring Conference Paper uri icon

abstract

  • Abstract: We present the first demonstration of an electrochemically-active biomaterial probe for schizophrenia treatment monitoring, and its integration in lab-on-a-chip devices. The probe consists of the naturally derived polymer, chitosan, grafted with catechol to provide a redox cycling system. These modifications to the probe significantly amplify the electrochemical signal generated by the antipsychotic drug clozapine, improving the signal- to-noise ratio and overall biosensing performance. The amplified signal generated by …

publication date

  • June 16, 2013