425: Prenatal exposure to isolated amniotic fluid disorders and the risk for long term cardiovascular morbidity in the offspring Academic Article uri icon


  • Objective Amniotic fluid abnormalities are often associated with adverse pregnancy outcomes, some of which are cardiovascular-related. We sought to assess whether in-utero exposure to amniotic fluid abnormalities increases the risk of long-term cardiovascular offspring morbidity. Study Design In a population based cohort study, the incidence of cardiovascular disorders was compared between singletons exposed and non-exposed to isolated oligohydramnios (defined as amniotic fluid index< 5) or polyhydramnios (defined as amniotic fluid index 25<). Cardiovascular morbidity was assessed up to the age of 18 years according to a predefined set of ICD-9 codes associated with hospitalization of the offspring. Multiple gestations, mothers with diabetes or hypertensive disorders, lack of prenatal care, and children with congenital malformations and chromosomal abnormalities, were …

publication date

  • January 1, 2018