Photo-switchable Microbial Fuel-Cells Academic Article uri icon


  • Abstract Regulation of Biosystems in a clean, simple and efficient way is important for the design of smart bio-interfaces and bioelecronic devices. Light as a non-invasive mean to control the activity of a protein enables spatial and temporal control far superior to other chemical and physical methods. The ability to regulate the activity of a catalytic enzyme in a biofuel-cell reduces the waste of resources and energy and turns the fuel-cell into a smart and more efficient device for power generation. Here we present a microbial-fuel-cell based on a surface displayed, photo-switchable alcohol dehydrogenase. The enzyme was modified near the active site using non-canonical amino acids and a small photo-reactive molecule, which enables reversible control over enzymatic activity. Depending on the modification site, the enzyme exhibits reversible behaviour upon irradiation with UV and …

publication date

  • February 7, 2018