Editorial [Hot topic: Membrane Interactions of Amyloid Proteins and Peptides (Guest Editor: Raz Jelinek)] Academic Article uri icon

abstract

  • The growing interest in membrane interactions of amyloidogenic peptides and proteins emanates from the realization that lipids and membranes play important, potentially central, roles in the toxicity and pathological pathways of amyloid diseases. Expanding body of evidence indicates that lipid binding of amyloidogenic peptides, and amyloid peptide association with cellular membranes are critical to the onset and progression of amyloid diseases. Conversely, membranes and membrane components appear to intimately affect the aggregation properties, and consequently the biological functions, of varied amyloidogenic proteins. This special issue of CPPS aims to provide an overview of important aspects on the cutting edge of this field. This Issue encompasses contributions from leading researchers, focusing on central phenomena involving aspects pertaining to …

publication date

  • January 1, 2010