149: Grand-multiparity in patients with an unscarred uterus and the risk for uterine rupture: A multicenter cohort study Academic Article uri icon


  • Objective Uterine rupture is a rare but critical complication. This multicenter cohort study aimed to determine whether grand-multiparity is a risk factor for uterine rupture in patients with an unscarred uterus. Study Design A comparison was performed between all singleton deliveries of grandmultiparous (defined as parity of 6 and higher) and singleton deliveries of parous women with 2-5 deliveries. Deliveries occurred between the years 2003-2015 in three medical centers. Patients with previous cesarean deliveries were excluded from the analysis. Multivariable analysis was used to control for confounders. Results: A total of 50,334 deliveries of grandmultiparous women were compared with a cohort of 338,456 deliveries with parity of 2-5. Grandmultiparae were significantly older (33.9+/-4.7 versus 27.3+/-5.2 years; P<. 0001) and their newborns had higher birth-weight as compared with …

publication date

  • January 1, 2018