Electronic Notifications about Drug Substitutes Can Change Physician Prescription Habits: A Cross-Sectional Observational Study Academic Article uri icon


  • Background: A health maintenance organization (HMO) provides physicians with electronic notifications regarding HMO-recommended drug substitutes. Objective: Investigating factors affecting physicians’ compliance and evaluating associated cost savings. Design: A cross-sectional observational study of all physicians in the HMO’s clinics from June 2005 to February 2006. Setting: Recording physician ID, initial drug choice, final drug choice, elapsed time between initial and final choices, and pharmacological details. Participants: Out of 2120 physicians, 647 physicians met the inclusion criteria. They prescribed 1.21 million prescriptions. Intervention: Transparently recording physicians’ response to HMO-recommended drug substitutes within a drug-prescription sub-system of an electronic medical record. Measurements: Compliance pattern, factors affecting compliance, and cost savings associated with compliance. Results: Thirty percent of prescriptions did not comply with substitute recommendations. Compliance ...

publication date

  • January 1, 2011