OC34: Lung volume measurements by 3D ultrasound are not superior to biometry by 2D ultrasound to predict pulmonary hypoplasia in fetuses with musculoskeletal... Academic Article uri icon


  • Objective This study compared the diagnostic efficiency of lung volume measurements by 3DUS with that of biometric parameters measured by 2D ultrasound (2DUS) in the identification of lethal pulmonary hypoplasia in fetuses with musculoskeletal disorders. Methods Volumes of the fetal chest from 85 fetuses with musculoskeletal disorders (lethal and non-lethal) examined before 32 weeks were reviewed. Lung and heart volumes were measured with VOCAL™. Chest circumference (CC), chest area (CA), rib cage perimeter (RCP), lung area (LA), heart area (HA), right lung diameter (RLD), lung length, abdominal circumference (AC), and femur length (FL) were measured by 2DUS. Pulmonary hypoplasia was confirmed by: 1) lung/body weight ratio⩽ 0.015< 28 weeks, or⩽ 0.012≥ 28 weeks of gestation, and/or 2) autopsy. Sensitivity, specificity, positive-and negative predictive …

publication date

  • September 1, 2006