The effect of previous antibiotic treatment for acute otitis media on the bacteriological resistance pattern of middle ear isolates Academic Article uri icon


  • Oral cephalosporin is often recommended for children who failed antibiotic treatment for AOM. In view of the increasing antibiotic resistance, mainly pneumococcus, we conducted a prospective study to assess the effect of previously antibiotic treatment (PAT) on MIC of pneumococci and H. influenzae isolates from middle ear fluid (MEF) in AOM. One hundred forty-three children with culture-proven AOM were prospectively studied (74 pneumococci; 91 H. influenzae). Forty-two (29%) received PAT, with several antibiotics for variable …

publication date

  • August 1, 1997