Our laboratory focuses on Mitochondrial genomics and evolution. We ask several research questions: 1. What and how is the functional contribution of inherited and acquired genetic variants in the mitochondrial and nuclear genome? 2. What is the underlying mechanism of coordinated regulation of the mitochondrial and nuclear genomes? 3. What does the evolutionary dynamics of mutations and genomic rearrangements in the mitochondrial and nuclear genome teach us about major evolutionary processes? 4. How can we use novel sequencing technologies to study the molecular basis of mitochondrial gene expression regulation? 5. Is the mitochondrial genome arranged in a similar higher order organization to bacteria? Nuclear chromatin?
located in facility
Marcus Campus 40-Toman Building for Life Sciences 0 009